SubtiBank SubtiBank
Version comparison:

2019-04-14 15:06:202025-05-23 11:26:59

locus

BSU18100

BSU_18100

outlinks

bsu

BSU18100

BSU_18100

Gene

Phenotypes of a mutant

essential [Pubmed|12682299]

a ''parC'' point mutation has been isolated upon selction at low pressure [Pubmed|26296725]

essential [Pubmed|12682299]

a ''parC'' point mutation has been isolated upon selction at low pressure [Pubmed|26296725]

upon overexpression, topoisomerase IV ([[protein|ParE]]-[[protein|ParC]]) can take over the functions of the type 1A topoisomerases [[protein|TopA]] and [[protein|TopB]] [pubmed|30957856]

The protein

Protein family

Topoisomerase IIA [[protein|GyrA]]/[[protein|ParC]] subunit family (together with [[protein|GyrA]]) (according to Swiss-Prot)

Topoisomerase IIA [[protein|GyrA]]/[[protein|ParC]] subunit family (together with [[protein|GyrA]]) (according to UniProt)

References

Original publications

16272394, 15466871, 16267290, 16479537, 9539793, 26296725, 12767818, 10713132, 9334322, 8940171, 7590259, 109442141330320, 12857958, 11090135, 8104339, 8227000, 30222737

16272394, 15466871, 16267290, 16479537, 9539793, 26296725, 12767818, 10713132, 9334322, 8940171, 7590259, 109442141330320, 12857958, 11090135, 8104339, 8227000, 30222737, 30957856

The protein

Catalyzed reaction/ biological activity

ATP-dependent breakage, passage and rejoining of double-stranded DNA (according to UniProt)